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Arizona Cardinals vs San Francisco 49ers Odds and Pick

The NFL’s third-leading passer, Carson Palmer (3,066 yards, 27 TDs), and third-leading passer, Carson Palmer (3,066 yards, 27 TDs), will be on display when the Arizona Cardinals (8-2) meet the San Francisco 49ers (3-7). The game starts at 4:05 p.m. ET on Sunday, Nov 29 and can be seen on FOX.

The Week 3 matchup between the 49ers and the Cardinals ended in a 47-7 loss for San Francisco. Kenneth Acker led the way for the 49ers defense in that game, totaling six tackles and one interception. Larry Fitzgerald had a big performance for Arizona, registering nine catches for 134 yards and two TDs. Chris Johnson had a big game as well, totaling 110 yards and two TDs on 22 attempts.

Arizona is a heavy eight-point favorite in this game and the Over/Under (O/U) is set at 44 points.

The 49ers enter the game with records of 3-7 Straight Up (SU) and 4-6 Against The Spread (ATS) this season. In the past five games, San Francisco is 2-3 for both SU and ATS. The 49ers tend to tread carefully when they play in their home city. They average a mere five penalties per home game, making them one of the least penalized teams in the league (third).

As for their opponent, the Cardinals have 8-2 SU and 6-4 ATS records this season. The Cardinals went 4-1 SU and 2-3 ATS over the last five games. Arizona has found a lot of success through the air. Its 297.6 passing yards per game ranks fourth in the NFL. The Cardinals look to exploit San Francisco’s inept offense, which averages a league-worst 13.6 points per home game. The Cardinals could have a favorable matchup, because San Francisco’s passing game has not been reliable this year. The 49ers rank 30th in the league with 188.1 passing yards per game. The Cardinals don’t waste time early in the game, averaging 5.9 points in the first quarter this year. San Francisco tends to lose the time of possession battle during home games, averaging a time of 27:37 for 31st in the league.

Predictions: SU Winner – Ari, ATS Winner – Ari, O/U – Under

Notes

San Francisco is 4-12 ATS in its last 16 games.

San Francisco is 2-7 SU in its last 9 games.

The total has gone UNDER in 5 of San Francisco’s last 6 games at home.

San Francisco is 4-2 SU in its last 6 games at home.

San Francisco is 4-11 ATS in its last 15 games at home.

The total has gone OVER in 4 of San Francisco’s last 6 games when playing Arizona.

San Francisco is 10-3 SU in its last 13 games when playing Arizona.

San Francisco is 2-4 ATS in its last 6 games when playing Arizona.

Arizona is 6-1 SU this season, when leading at the half. San Francisco is 3-0 SU when taking a lead into halftime.

This season, Arizona is 3-2 SU in games where it wins the turnover battle, yet undefeated (3-0 SU) in games where it loses the turnover battle.

Dating back to last year, Arizona is an even 5-5 SU against NFC West opponents, while San Francisco is just 2-8 SU against division foes.

Arizona is rated higher in the ground game on both sides of the ball. Its 10th-ranked rushing attack will face the 27th-ranked run defense of San Francisco, while its seventh-ranked run defense will look to contain the 18th-ranked rushing game of the 49ers.

Written by GMS Previews

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