Week 6 of the NFL season presents our first action overseas. The Oakland Raiders and Seattle Seahawks will clash in London — we’ll go over the line for that matchup as well as every other contest for NFL Week 6:
Related: NFL Betting Guide
Philadelphia Eagles at New York Giants
Opening Odds: Eagles -2.5
How good are the Eagles? They have now lost three of their last four games with their defense giving up at least 23 points in each contest. They are a 2.5-point favorite in this spot but they have just one more win than the Giants this season.
Arizona Cardinals at Minnesota Vikings
Opening Odds: Vikings -9.5
The Cardinals earned their first win of the season in San Francisco. They figure to have a much tougher time this week against a Vikings team that looks like they’ve woken up. Minnesota earned a quality win in Philadelphia in Week 5.
Chicago Bears at Miami Dolphins
Opening Odds: Bears -2
The Dolphins have crumpled over the last two weeks. First, they were blown out by the New England Patriots and then they blew a 17-3 second half lead in Cincinnati. Their 3-0 start has long been forgotten.
Carolina Panthers at Washington Redskins
Opening Odds: Redskins -2
The Redskins return off their bye week to host Carolina. The Panthers were very lucky to escape Week 5 with a win over the New York Giants. They needed a last-second 63-yard field goal to edge them out.
Pittsburgh Steelers at Cincinnati Bengals
Opening Odds: Bengals -3
They don’t get much love, but the Bengals are a healthy 4-1 this season with their only loss coming at Carolina. Pittsburgh continues to be sloppy but they can get right back in the division race with a win here.
Tampa Bay Buccaneers at Atlanta Falcons
Opening Odds: Falcons -3.5
Once viewed as a playoff contender, the Falcons are nothing short of a disaster at 1-4. They’ll host the Bucs in this spot, who are coming off a bye week.
Kansas City Chiefs at New England Patriots
Opening Odds: Patriots -3.5
This will be the marquee matchup of the week. The Chiefs have yet to lose, while the Patriots are back in a groove after winning their last two games by a combined score of 76-31.
Buffalo Bills at Houston Texans
Opening Odds: Texans -8.5
The Bills have been a Jekyll-Hyde team this season, beating the Tennessee Titans and Minnesota Vikings, but also getting smoked by the Los Angeles Chargers, Green Bay Packers and Baltimore Ravens. They’re a big dog at Houston this week.
Los Angeles Rams at Denver Broncos
Opening Odds: Rams -6.5
The Rams are a perfect 5-0 and face a reeling Broncos team that’s lost four in a row. Keep in mind that the Rams might be shorthanded here as receivers Cooper Kupp and Brandin Cooks suffered concussions last week.
Baltimore Ravens at Tennessee Titans
Opening Odds: Ravens -2
It feels like these two teams will be fighting for a wild card berth at the end of the season, so this matchup is important. Both teams lost as road favorites in Week 5.
Jacksonville Jaguars at Dallas Cowboys
Opening Odds: Jaguars -2
The Jaguars defense was shredded by Kansas City last week. They have a much more manageable task in front of them in Dallas this week.
Other Opening Odds:
San Francisco 49ers at Green Bay Packers
Opening Odds: Packers -7.5
Los Angeles Chargers at Cleveland Browns
Opening Odds: Chargers -1
Indianapolis Colts at New York Jets
Opening Odds: Jets -2.5
Seattle Seahawks at Oakland Raiders
Opening Odds: Seahawks -2